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it would be nice to define the global configurations in ewcfg in a way that devs can modify them at run time need be,some use cases can be to allow the generated application to also extend it settings to be modifiable by final users as long as the dev gives them some table with settings to match some globalconfigurations, that way we can modify them at runtime

You can use the new Config() function in v2020, see Some Global Functions in Server Events and Client Scripts of the help file.